The Last Furlong

Comments on the race of life.

Diabetes Types 1,2,3 and now 4

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The Furlongs in this house, are trying to overcome Type 2 Diabetes in various ways. But now I see there is new stuff coming out on Diabetes which I’ll share with you. No matter what science discovers in the “how and why” department, and what pills the Drug Companies peddle, in the end, I guess it will all come down to FOOD. Dammit. 

Type 1 diabetes mellitus (T1DM) is caused by destruction (usually autoimmune) of pancreatic islet beta cells and attendant insulin deficiency.

Type 2 diabetes mellitus (T2DM), the most common form, is caused by insulin resistance in peripheral tissues and is most frequently associated with aging, a family history of diabetes, obesity, and failure to exercise.

Type 3 diabetes mellitus (T3DM, discussed later) corresponds to a chronic insulin resistance plus insulin deficiency state that is largely confined to the brain but, like NASH, can overlap with T2DM. We have proposed that T3DM represents a major pathogenic mechanism of AD neurodegeneration

In other words – Alzheimer’s Disease is Type 3 Diabetes


But that is not all!

The findings (of the Salk Institute) , published in the journal Nature, call for a new kind of diabetes classification: type 4 diabetes.

> Evans wanted to investigate why thin, older people can develop type 2 diabetes without weight gain

> Evans said: “A lot of diabetes in the elderly goes undiagnosed because they don’t have the classical risk factors for type 2 diabetes, such as obesity. It turns out that for this type of diabetes, the treatment is not losing weight. The treatment is actually losing these cells, and we show that it’s possible to do that.

“We hope our discovery not only leads to therapeutics, but to an increased recognition of type 4 diabetes as a distinct disease.”



Author: thelastfurlong

I'm someone also pounding the Path, just like you.. I'm retired, going into Old Age and loving my life. I'm hoping to remain happy and well for as long as possible. Old Age is not SO bad - yet!

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